To profile the chromatin structural changes reprogrammed by the liquid-liquid phase separation of DAXX [HiChIP]
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https://www.ncbi.nlm.nih.gov/sra/SRP418331
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资源简介:
DAXX is an epigenetic regulator and chromatin chaperon protein. This experiment aims to investigate whether DAXX's phase separation causes changes in chromatin structures. Overall design: DAXX was fused with a Cry2 domain which enables DAXX to form condensates upon blue light illumination. HiChIP was employed to profile the long-range chramatin interactions in HEK293 cells expressing DAXX-mCherry-Cry2 with or without blue light illumination.
创建时间:
2023-05-13



