The c-Src/LIST positive feedback loop sustains tumor progression and chemoresistance
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https://www.ncbi.nlm.nih.gov/sra/SRP429959
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资源简介：
Chemotherapy resistance and treatment failure hinder clinical cancer treatment. Src, the first mammalian proto-oncogene to be discovered, is a valuable anti-cancer therapeutic target. Several c-Src inhibitors have reached the clinical stage, but drug resistance remains a challenge during treatment. Herein, we uncovered a positive feedback loop between a previously uncharacterized long non-coding RNA (lncRNA), which we renamed LncRNA Inducing c-Src Tumor-Promoting Function (LIST), and c-Src.
创建时间：
2023-03-30
