E2F6:TFDP1 binds to MGA:MAX
收藏reactome.org2025-03-23 收录
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The E2F6 heterodimer with TFDP1 forms a complex with the heterodimer of MGA and MAX transcription factors. The E2F6:TFDP1:MGA:MAX complex is the core of the E2F6.com-1 complex and is able to bind to E2F, Myc and Brachyury (T box) binding elements in DNA (Ogawa et al. 2002).
E2F6异源二聚体与TFDP1结合,形成与MGA和MAX转录因子异源二聚体复合的结构。E2F6:TFDP1:MGA:MAX复合体构成E2F6.com-1复合体的核心,并能与DNA中的E2F、Myc以及Brachyury(T盒)结合元件相结合(Ogawa等,2002年)。
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