E2F6:TFDP1 binds to MGA:MAX

The E2F6 heterodimer with TFDP1 forms a complex with the heterodimer of MGA and MAX transcription factors. The E2F6:TFDP1:MGA:MAX complex is the core of the E2F6.com-1 complex and is able to bind to E2F, Myc and Brachyury (T box) binding elements in DNA (Ogawa et al. 2002).E2F6异源二聚体与TFDP1结合，形成与MGA和MAX转录因子异源二聚体复合的结构。E2F6:TFDP1:MGA:MAX复合体构成E2F6.com-1复合体的核心，并能与DNA中的E2F、Myc以及Brachyury（T盒）结合元件相结合（Ogawa等，2002年）。