**Overview**
This data package contains the details of substances in drugs, biologics, foods and devices registered with a Unique Ingredient Identifier (UNII) through the joint FDA/USP Substance Registration System (SRS). It also contains a list of the names used for each UNII and the changes made to Unique Ingredient Identifiers' (UNIIs) descriptions to the latest update.
**Description**
The Unique Ingredient Identifier (UNII) is a non-proprietary, free, unique, unambiguous, non-semantic, alphanumeric identifier based on a substance's molecular structure and/or descriptive information. The UNII is:
- One of the core components of the United States Federal Medication Terminology.
- Used in the FDA's Structured Product Labeling
- Used to assist in the generation of the National Library of Medicine's (NLM's) RxNorm.
- A US government standard for drug ingredient and food allergen identifiers
- A component of the Environmental Protection Agency's Substance Registry System (future) The overall purpose of the joint FDA/USP Substance Registration System (SRS) is to support health information technology initiatives by generating unique ingredient identifiers (UNIIs) for substances in drugs, biologics, foods, and devices.
The UNII is a non- proprietary, free, unique, unambiguous, non-semantic, alphanumeric identifier based on a substance’s molecular structure and/or descriptive information. The procedures and management of the SRS is provided by the SRS Board. The SRS Board includes experts from both FDA and USP. The SRS operating procedures defined by the SRS Board are detailed in the SRS Manual. The UNII is a core component of the US Federal Medication Terminology, it is used for product labeling, to assist in the generation of RxNorm, as an identifier for drug ingredients and allergens and in the future will be a component of the Environmental Protection Agency's Substance Registry System. The UII is useful for understanding data contained in NLM's Unified Medical Language System, National Cancer Institute Enterprise Vocabulary Service, FDA Data Standards Council website, VA National Drug File Reference Terminology, FDA Inactive Ingredient Query Application and, proximately, USP Dictionary of USAN and International Drug Names.
**Benefits**
- The overall purpose of the joint fda/usp substance registration system (srs) is to support health information technology initiatives by generating unique ingredient identifiers (uniis) for substances in drugs, biologics, foods, and devices.
**License Information**
The use of John Snow Labs datasets is free for personal and research purposes. For commercial use please subscribe to the [Data Library](https://www.johnsnowlabs.com/marketplace/) on John Snow Labs website. The subscription will allow you to use all John Snow Labs datasets and data packages for commercial purposes.
**Included Datasets**
- [Unique Ingredient Identifier Changes](https://www.johnsnowlabs.com/marketplace/unique-ingredient-identifier-changes)
- This dataset displays the changes made to Unique Ingredient Identifiers' (UNIIs) descriptions to the lastest update (2019). Content in this dataset is related to the Unique Ingredient Identifier Records dataset.
- [Unique Ingredient Identifier Names](https://www.johnsnowlabs.com/marketplace/unique-ingredient-identifier-names)
- This dataset contains a list of the names used for each UNII (Unique Ingredient Identifier). Contents on this dataset are related to the UNII Records dataset.
- [Unique Ingredient Identifier Records](https://www.johnsnowlabs.com/marketplace/unique-ingredient-identifier-records)
- This dataset contains the details of substances in drugs, biologics, foods and devices registered with a Unique Ingredient Identifier (UNII) through the joint FDA/USP Substance Registration System (SRS).
**Data Engineering Overview**
**We deliver high-quality data**
- Each dataset goes through 3 levels of quality review
- 2 Manual reviews are done by domain experts
- Then, an automated set of 60+ validations enforces every datum matches metadata & defined constraints
- Data is normalized into one unified type system
- All dates, unites, codes, currencies look the same
- All null values are normalized to the same value
- All dataset and field names are SQL and Hive compliant
- Data and Metadata
- Data is available in both CSV and Apache Parquet format, optimized for high read performance on distributed Hadoop, Spark & MPP clusters
- Metadata is provided in the open Frictionless Data standard, and its every field is normalized & validated
- Data Updates
- Data updates support replace-on-update: outdated foreign keys are deprecated, not deleted
**Our data is curated and enriched by domain experts**
Each dataset is manually curated by our team of doctors, pharmacists, public health & medical billing experts:
- Field names, descriptions, and normalized values are chosen by people who actually understand their meaning
- Healthcare & life science experts add categories, search keywords, descriptions and more to each dataset
- Both manual and automated data enrichment supported for clinical codes, providers, drugs, and geo-locations
- The data is always kept up to date – even when the source requires manual effort to get updates
- Support for data subscribers is provided directly by the domain experts who curated the data sets
- Every data source’s license is manually verified to allow for royalty-free commercial use and redistribution.
**Need Help?**
If you have questions about our products, contact us at [info@johnsnowlabs.com](mailto:info@johnsnowlabs.com).