Mutation rate at the <i>HIS3 CAN1</i> cassette in mitotic and meiotic cell divisions.

1Ploidy H-haploid, D-diploid. 2Only relevant genotypes are shown, see Table 1 for full genotype. 3Values in parentheses are 95% confidence intervals (calculated as described in Materials and Methods). 4Mitotic rates calculated by MSS-MLE method [64], see Materials and Methods. 5Meiotic rates calculated as described in Materials and Methods. 6Meiosis/Mitosis is the calculated meiotic rate divided by the calculated mitotic rate to provide fold difference. 7NA- not applicable: haploids and spo11/spo11 diploids are unable to sporulate. Mutation rate at the HIS3 CAN1 cassette in mitotic and meiotic cell divisions.