Transcriptome analysis of overexpressed SNCA in differentiated SH-SY5Y neuroblastoma cells
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
The goal of this study is to compare NGS-derived transcriptome profiling (RNA-seq) of alpha-synuclein expressing Sh-SY5Y cells vs. lacZ control protein and find characteristic changes that may be related to alpha-synucleinopathies. Our results showed the enrichments of p53 pathways, DNA damage responses, and cellular senescence. Further studies validated genes involved in such pathways. To obtain transcriptome profiling after ectopic SNCA expression.
创建时间：
2022-03-10
