Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2. Wu et al.

Name: Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2. Wu et al.
Creator: Donglai Wang
Published: 2026-04-09T12:26:27+08:00

Mendeley Data2026-04-09 收录

PD-1蛋白调控

免疫检查点分子机制

数据链接：

https://data.mendeley.com/datasets/rtv4bf8br6 数据链接链接失效反馈

官方服务：

资源简介：

This dataset contains the raw data of all images and all quantitative/statistical analyses.

提供机构：

Donglai Wang

Cooperation between ZEB2 and SP1 upregulates PD-L1 and CCL2 to promote the immunosuppressive activity of tumor cells

肿瘤免疫微环境

免疫检查点分子机制

Epithelial-mesenchymal transition (EMT) is implicated in tumor progression, and EMT-inducing transcription factors play multifaceted roles; however, the molecular mechanisms underlying these processes

NIAID Data Ecosystem50

Gene signature profiles in lung tisses of wild type mice or PD-1 or PD-L1 deficient mice infected with Mycobacterium avium

免疫检查点分子机制

感染免疫转录组学

Rationale: T cell activation is a key antimicrobial component against mycobacterial disease. Programmed cell death-1 (PD-1) and programmed cell death-ligand 1 (PD-L1) pathway could affect the antimicr

NIAID Data Ecosystem30

Siglec-9 acts as an immune checkpoint molecule on macrophages in glioblastoma, restricting T cell priming and immunotherapy response [bulk RNA-seq]

胶质母细胞瘤免疫治疗

免疫检查点分子机制

The neoadjuvant immune checkpoint blockade therapy only benefits a limited fraction of glioblastoma multiforme (GBM) patients. Thus, targeting other immunomodulators on myeloid cells is an attractive

NIAID Data Ecosystem00

Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

HIV相关心血管风险

免疫检查点分子机制

Recent findings point to a role of Checkpoint Inhibitor (CPI) receptors at the tissue level in immune homeostasis. Here we investigated the role of CPI molecules on immune cells in relation to cardiac

NIAID Data Ecosystem50

Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells

T细胞调控

免疫检查点分子机制

Effector T cells comprise the cellular arm of the adaptive immune system and are essential for mounting immune responses against pathogens and cancer. To reach effector status, costimulation through C

Figshare2021-09-22 更新10

Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2. Wu et al.

资源简介：

相关数据集