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Obesity Remodels Activity and Transcriptional State of a Lateral Hypothalamic Brake on Feeding

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NIAID Data Ecosystem2026-04-25 收录
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We demonstrate that high fat diet (HFD)-induced obesity alters the transcriptional state of lateral hypothalamic glutamate neurons in mice. Overall design: High-throughput single-cell RNA sequencing of lateral hypothalamic area (LHA) tissue in mice given ad libitum access to HFD or taste-matched control chow.

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2020-01-07
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