The H3K27 demethylase Utx facilitates somatic and germ cell epigenetic reprogramming to pluripotency

ChEBI2012-05-29 更新2026-07-21 收录

表观遗传重编程

干细胞多能性

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The H3K27 demethylase Utx facilitates somatic and germ cell epigenetic reprogramming to pluripotency

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2012-05-29

Shigella induces epigenetic reprogramming of zebrafish neutrophils

训练免疫

表观遗传重编程

Trained immunity is a long-term memory of innate immune cells, generating an improved response upon re-infection. Shigella is an important human pathogen and inflammatory paradigm for which there is n

NIAID Data Ecosystem90

Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion. Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion

X染色体再激活

表观遗传重编程

In female mammals, one of the two X chromosomes is silenced as pluripotent cells differentiate. This process, termed X-inactivation, is random and results in mosaic expression of many X-linked genes i

NIAID Data Ecosystem40

RNA-seq of naive and primed ES cells. Homo sapiens

干细胞多能性

转录组学分析

Here we propose a set of molecular criteria for evaluating the naive human pluripotent state. We show by RNA-seq that transcription of transposable elements provides a sensitive measure of the concord

NIAID Data Ecosystem30

Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

受精卵DNA去甲基化

表观遗传重编程

The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential.

NIAID Data Ecosystem50

HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]. HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]

红细胞生成低氧应答

表观遗传重编程

We performed RNA-sequencing on erythropoietic cells cultured in normoxia or hypoxia at days 3,7, and 10. We found numerous expression changes induced by hypoxia, including the canonical hypoxia target

NIAID Data Ecosystem40

The H3K27 demethylase Utx facilitates somatic and germ cell epigenetic reprogramming to pluripotency

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