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Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases

NIAID Data Ecosystem2026-05-02 收录

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适体药物开发

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Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases

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创建时间：

2024-11-20

补体系统抑制

蛋白质复合物结构解析

Structure of complement C5 in complex with SSL7 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM I

Protein Data Bank Japan2024-11-06 更新100

Supplementary Material for: Precision Treatment of IgA Nephropathy Based on a New Framework: Angiorenal Protection, Immunity Inhibition, B-Cell/Plasma-Cell Modulation, and Complement Inhibition

免疫调节疗法

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Medicine

DataCite Commons2025-06-01 更新80

Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D

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病毒结构免疫学

Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D Descriptor: Anti-Factor D, heavy chain, light chain, ... Authors: Murray, J.M, Wiesmann, C. Deposit date: 2012

Protein Data Bank Japan2024-10-09 更新30

Structure of an anophensin from Anopheles stephensi

蚊子唾液

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Structure of an anophensin from Anopheles stephensi Descriptor: Anophensin Authors: Andersen, J.F, Strayer, E, Lu, S. Deposit date: 2020-06-30 Release date: 2021-05-05 Last modified: 2024-11-06 Method

Protein Data Bank Japan2024-11-06 更新80

C1-inactivator is upregulated in glioblastoma

胶质瘤免疫逃逸

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Background Glioblastoma is the most common and aggressive type of primary brain tumor in adults. A key problem is the capacity of glioma cells to inactivate the body’s immune response. The complement

NIAID Data Ecosystem40

Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases

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