Additional file 6 of Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder
Supplemental material, sj-xlsx-5-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep depriv
What governs the concentrations of metabolites within living cells? Beyond specific metabolic and enzymatic considerations, are there global trends that affect their values? We hypothesize that the ph
Each row is a replicate in which KO indicated ENH5 knockout and WT indicates a vehicle treated wildtype line. All cells come from individual CHB633. (XLSX)
BackgroundEstrogen homeostasis is crucial for bladder function, and estrogen deprivation resulting from menopause, ovariectomy or ovarian dysfunction may lead to various bladder dysfunctions. However,
BackgroundImmunotherapy combined with chemotherapy has improved outcomes in advanced gastric cancer (GC), but reliable biomarkers to predict clinical benefit remain limited. Metabolomics provides a co
