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Pharmacological Activation of STING blocks SARS-CoV-2 infection. Pharmacological Activation of STING blocks SARS-CoV-2 infection

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA699591
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We infected Calu3 cells (derived from human lung epithelium) with SARS-CoV-2 for 24 and 48 hours. Calu3 cells were also treated with the STING agonist diABZI for 6 and 12 hours. Finally, heterozygous K18-hACE c57BL/6J mice were treated with diABZI for 6 and 12 hours and lung tissue was harvested for sequencing. Overall design: Calu3 cells infected were infected with SARS-CoV-2 or treated with diABZI. Mice were treated with diABZI and lungs were harvested for sequencing.
创建时间:
2021-02-04
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