POSTN secreted from glioblastoma stem cells can recruit microglia and upregulate CD70 expression in microglia through the αVβ3/PI3K/AKT/NFκB pathway
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE273464
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资源简介：
Our findings revealed that POSTN secreted from GSCs can recruit microglia and upregulate CD70 expression in microglia through the αVβ3/PI3K/AKT/NFκB pathway, which in turn promotes Treg development and functionality and supports the formation of an immunosuppressive tumor microenvironment. Comparative gene expression profiling analysis of RNA-seg data of HMC3 cells treated with PBS or human recombinant POSTN.
创建时间：
2024-10-01
