Different conformations of RNA-dependent RNA polymerase of SARS-CoV-2 under different experimental conditions

Proteins do not exist in isolation in the cellular milieu. Often, they are bound to other proteins, cofactors, or are influenced by the prevailing physicochemical conditions to be under different conformations. This work collates four different experimental structures of RNA-dependent RNA polymerase of SARS-CoV-2 deposited at the Protein Data Bank. Obtained under different experimental conditions such as with and without reducing conditions, or pre- or post-translocation, the presented structures should be useful for further analysis of the functional role of RNA-dependent RNA polymerase in the pathogenesis of SARS-CoV-2.