官方服务:
资源简介:
Analysis outcome of DNA repair
应用场景:
创建时间:
2017-04-26
相关数据集
'构建基因编辑工具鼠,并用已知功能的致死基因验证体内基因敲除的有效性'的相关数据集
CRISPR-stop技术将蛋白质编码序列转化为终止密码子,从而在适当的位置产生了无效等位基因。CRISPR-stop在单细胞期合子中诱导产生Founder 0(F0)纯合突变体小鼠,这避免了小鼠繁殖并可作为非致命基因的快速筛选方法。然而哺乳动物25%的基因,其功能丧失会导致早期死亡。在这里,我们在二细胞期合子中的一个细胞进行CRISPR-stop操作,一种我们称之为嵌合型CRISPR-stop的
中国科学院脑科学数据中心2023-12-11 更新140
ENGINEERED NUCLEASES TO GENERATE MUTATIONS IN PLANTS
Methods are provided to mutate, in a targeted manner, the genome of a plant cell using a double stranded DNA break inducing enzyme. Also provided are plants, in particular Brassica plants that yield
国家林业和草原科学数据中心2023-02-12 更新80
Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm (XEN) cells from pig blastocysts
We report for the first time, the derivation and characterization of extra-embryonic endoderm (XEN) cells from primitive endoderm (PrE) of porcine (p) embryos. The pXEN cells can be reliably and repro
干细胞与再生医学数据中心2022-02-20 更新60
Broad Institute CRISPR Patent Licenses and Press Releases
This dataset contains PDFs of CRISPR patent licenses, and press releases containing patent license information, originating from the Broad Institute, Cambridge, MA.
DataONE2017-02-15 更新80
Methods for plant transformation
The methods disclosed herein use a morphogenic gene or a repressor gene to provide a transgenic plant containing a single copy of a transgenic event wherein the morphogenic gene or the repressor gene
国家林业和草原科学数据中心2023-02-12 更新70



