Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with inhibitor

Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with inhibitor Descriptor: 1,2-ETHANEDIOL, 5-chloranyl-6-[1-[(3-fluorophenyl)methyl]pyrazol-4-yl]pyrimidin-4-amine, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ... Authors: Thomas, S.E, Charoensutthivarakul, S, Coyne, A.G, Abell, C, Blundell, T.L. Deposit date: 2020-05-04 Release date: 2021-05-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.274 Å) Cite: Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach. Acs Infect Dis., 8, 2022