Supplementary Material for: Late onset Sub-Retinal Silicone Oil Migration through Optic Disc Coloboma

This report describes a case of late onset subretinal silicone oil migration in an eye with congenital optic disc coloboma and its treatment. A 15-year-old male with a history of left eye congenital optic disc coloboma and amblyopia presented with a third recurrence of retinal detachment (RD) with proliferative vitreoretinopathy (PVR). The patient underwent PPV, subretinal fluid drainage through a peripheral retinotomy, silicone oil tamponade, and endolaser around the coloboma and retinotomy. The retina re-attached successfully. However, 14 months post-operatively examination revealed high intra-ocular pressure (IOP) of 33 mmHg and a submacular bubble of silicone oil was evident. The patient underwent sub macular silicone oil removal. Here we describe the unique late onset subretinal migration of intravitreal silicone oil following retinal detachment repair in an eye with optic disc coloboma in association with raised IOP. Silicone oil in the presence of optic disc pit may have serious complications requiring clinician awareness, including, retrolaminar and intraventricular migration with potential vision loss and central nervous system toxicity. This case demonstrates potential mechanisms of sub retinal silicone oil migration through the coloboma that serves as a passage and an increased IOP which drives the oil from the vitreous in to the sub retinal space.