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Distinct SWI/SNF chromatin remodelling complexes act differentially to maintain stem-like exhausted CD8 T cells.. Distinct SWI/SNF chromatin remodelling complexes act differentially to maintain stem-like exhausted CD8 T cells.

NIAID Data Ecosystem2026-03-13 收录

T细胞耗竭

染色质重塑调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA870141 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-08-16

染色质重塑调控

伪常染色体基因转座

Pseudoautosomal regions (PAR1 and PAR2) in eutherians retain homologous regions between the X and Y chromosomes that play a critical role in the obligatory X-Y crossover during male meiosis. Genes th

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DEREGULATED INTRACELLULAR PATHWAYS DEFINE NOVEL MOLECULAR TARGETS FOR HBV-SPECIFIC CD8 T CELL RECONSTITUTION IN CHRONIC HEPATITIS B. DEREGULATED INTRACELLULAR PATHWAYS DEFINE NOVEL MOLECULAR TARGETS FOR HBV-SPECIFIC CD8 T CELL RECONSTITUTION IN CHRONIC HEPATITIS B

T细胞耗竭

慢性乙型肝炎免疫学

Background and aims: In chronic HBV infection elevated ROS levels by dysfunctional mitochondria can cause increased protein oxidation, proteostasis engulfment and DNA damage in exhausted virus-specifi

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Mcm2 promotes stem cell differentiation via its ability to bind H3-H4 (ChIP-Seq)

干细胞分化表观遗传学

染色质重塑调控

Mcm2, a subunit of the Mcm2-7 helicase best known for its role in DNA replication, contains a histone binding motif that facilitates the transfer of parental histone following DNA replication. Here we

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Ectopic Tcf1 expression reprograms exhausted CD8+ T cells to acquire stem cell-like features [RNA-seq]

T细胞耗竭

细胞重编程

The goal of this study is to determine the capacity of Tcf1 to reprogram exhausted CD8+ T cells for function restoration. Tex cells elicited by chronic infection contain a CXCR5+Tim3– subset that has

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scRNA-seq of antigen-specific CD8+ T cells from tumor draining LN, TIL and PBMC of melanoma bearing mice

肿瘤免疫

T细胞耗竭

CD8+ T cell-mediated immune response plays a pivotal role in controlling tumor growth.However, within the tumor microenvironment (TME), prolonged antigen exposure, as well as immunosuppressive factors

NIAID Data Ecosystem60

Distinct SWI/SNF chromatin remodelling complexes act differentially to maintain stem-like exhausted CD8 T cells.. Distinct SWI/SNF chromatin remodelling complexes act differentially to maintain stem-like exhausted CD8 T cells.

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