Polymer simulations guide the detection and quantification of chromatin loop extrusion by imaging

<strong>Dataset description</strong> This dataset contains coordinates of the two anchors of a 150 kb simulated loop. The subfolder 'Free' contains coordinates from a polymer not submitted to loop extrusion (1,000 independent simulations). The subfolder 'Loop' contains loop anchor coordinates in a polymer submitted to loop extrusion (4,000 independent simulations). In simulations with extrusion, the polymer chain was simulated such as it went through 3 different states : i) Open state (absence of loops) ii) Extruding state where the loop size increases with time (anchor-anchor distance decreases) and iii) Closed state corresponding to a stable loop with the two anchors in contact. <strong>Structure of data</strong> In each .txt file, the first three columns correspond to the XYZ coordinates of the anchor (in µm), the fourth column indicates the state label (0=Open, 1=Extruding, 2=Closed). Each row corresponds to a simulation timepoint (2991 timepoints in polymers submitted to loop extrusion). The simulation ID is indicated at the end of each .txt file. The two anchors of the loop are bead #275 and bead #324.