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Understanding the Basis of Resistance in the Irksome Lys103Asn HIV-1 Reverse Transcriptase Mutant through Targeted Molecular Dynamics Simulations

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Understanding_the_Basis_of_Resistance_in_the_Irksome_Lys103Asn_HIV_1_Reverse_Transcriptase_Mutant_through_Targeted_Molecular_Dynamics_Simulations/3313723
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Results of targeted molecular dynamics simulations confirm the existence of a higher energy barrier for creation of the pocket where non-nucleoside reverse transcriptase inhibitors bind in the K103N mutant enzyme relative to wild-type.
创建时间:
2016-05-06
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