External data associated with: ' Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1 '.

Dataset S1 

Proteome database. Table containing all eukaryotic species information from which sequences are used to construct the phylogenetic trees in SI Fig. S1A-H.

Dataset S2

Manually curated HMM of RING1, PCGF, EZH, RBBP, EED, and SUZ12.

Dataset S3

Materials that were used for the structural alignment. Includes TM align files, HHpred outputs and pdb files of excised C-terminal ß-hairpins. 

Dataset S4

Materials and Data that were used for the homology analyses of CBX, PHC, RYBP, and SUZ12. For CBX and RYBP, HMM profiles and HMMsearch outputs are provided. For PHC, SAM and MBT HMM profiles and searches, and newick files of our phylogenetic trees are provided. For SUZ12, HMM profile and multiple sequence alignment are provided. 

Dataset S5

Alphafold structures of putative sequences of RING and PCGF and the newly identified RYBP orthologs.

Dataset S6

Blastoutputs of RING, PCGF, EZH, EED, and RBBP.

Dataset S7

Multiple sequence alignments used to build phylogenetic trees and newick files for EZH, EED, RBBP, RING and PCGF.

Dataset S8

Fasta sequence files of our orthologous groups of the core subunits of PRC1 and PRC2, and newly identified ncPRC1 accessory subunits.