Cross-platform analysis of DENV host factors.

The number of host factors identified in each of the RNAi screens listed compared to the differentially regulated isoforms and differentially spliced genes for both the wild-type DENV1-16007 and vaccine strain DENV1-PDK13. Percentages of overlap are indicated in parenthesis. The unpublished DENV screen by Jamison SF, Garcia-Blanco, M.A. utilize the same siRNA library, cell line, general methodology and statistical analysis described in Le Sommer et al 2012. The unpublished hits from the WNV screen are the full, unannotated results from the published Krishnan et al 2008 study.