Suggestive and significant associations in the PXO recombinant inbred set.

Summary of quantitative trait loci identified in the PXO recombinant inbred rat panel. The letter “f” followed by a number (e.g. f5) corresponds to a particular fraction of lipoproteins as depicted in Figure 1. SNP (single nucleotide polymorphism) focusing column denotes the position of the QTL on the chromosome (Chr.) according to the Rat Genome V3.4 Assembly. % - percentage of trait variance explained by QTL, C – cholesterol, TG – triacylglycerols; LOD – likelihood of odds score (bold for genome-wide significance, italics for suggestive association); VLDL - very low-density lipoprotein; LDL - low density lipoprotein; HDL - high-density lipoprotein; wt – weight; adiposity index – calculated as epididymal (visceral) fat weight per 100 g of body weight; *…region contains known CNV distinct between SHR and BN-Lx[39]. The total number of genes within the QTL region is shown. Mean values ± SEM are shown for PXO strains carrying the SHR-Lx (SHR/SHR) allele vs. those carrying the BXH2/Cub allele (BN/BN) for the given trait and locus.
Suggestive and significant associations in the PXO recombinant inbred set.