Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
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Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity Descriptor: 4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide, GLYCEROL, Heat shock protein HSP 90-alpha Authors: Zuccola, H.J, Ernst, J. Deposit date: 2013-11-04 Release date: 2014-01-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Correlation between chemotype-dependent binding conformations of HSP90 alpha / beta and isoform selectivity-Implications for the structure-based design of HSP90 alpha / beta selective inhibitors for treating neurodegenerative diseases. Bioorg.Med.Chem.Lett., 24, 2014
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2013-11-04
