Regions of statistically significant differences of functional cerebral cortical activation as determined by SPM analysis.

Data are for rats with bilateral striatal lesions, sham lesions, during treadmill walking or at rest, and with or without a prior history of exercise training (Groups: Lesion/Walk/No-ET, n = 9; Sham/Walk/No-ET, n = 10; Lesion/Rest/No-ET, n = 10; Sham/Rest/No-ET, n = 9; Lesion/Walk/ET, n = 11; Lesion/Rest/ET, n = 12). Significance for all entries is shown at the voxel level (P<0.05) with a minimum extent threshold of 100 contiguous voxels. ‘a’ denotes ‘anterior’ and ‘p’ denotes ‘posterior’. ‘+’ denotes increases and ‘−’ denotes decreases in the group differences in cerebral blood flow tracer distribution in the left/right hemispheres, with symbols in parentheses denoting changes less broadly represented.