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Multiomic Analysis of Adult Diapause in Drosophila melanogaster Identifies Hallmarks of Cellular Quiescence [RNA-Seq]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE212863
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Diapause and diapause-like states constitute natural, inducible, and evolutionarily conserved examples of lifespan plasticity that are well-suited to represent physiologically accurate models for longevity. We integrated ATAC-seq and RNA-seq technologies to probe the transcriptional regulatory pathways controlling lifespan plasticity in diapause. Comparison of chromatin accessibility profiles from w1118 virgin female adult Drosophila in diapause or in regular conditions, additionally supplemented with either S-methoprene or ethanol (vehicle) for a total of 4 experimental conditions.
创建时间:
2022-12-21
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