Urease-Based Mucosal Immunization against Helicobacter heilmannii Infection Induces Corpus Atrophy in Mice
收藏PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC97018/
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资源简介：
Mucosal immunization with Helicobacter heilmannii urease B or Helicobacter pylori urease, given nasally with cholera toxin, protects BALB/c mice against H. heilmannii infection and significantly reduces a preexisting infection. However, immunization aggravates gastric corpus atrophy. Our results underline the necessity of defining immunization regimens that do not enhance mucosal damage.
提供机构：
American Society for Microbiology (ASM)
