Subgroup analyses for overall and progression-free survival for treatment with anti-EGFR drugs, comparing patients with increased versus not increased EGFR copynumber.

Subgroup analyses was performed when at least two studies were in each subgroup.Subgroup analysis was not performed for TTP as only three studies provided information for this outcome.FISH, fluorescent in situ hybridization; NA, not applicable; CI, confidence interval; HR, hazard ratio.