Homo sapiens Transcriptome or Gene expression. Homo sapiens

we collected and profiled PBMCs of healthy adults by carefully matching the ages of Asian donors. Computational pipelines for WGCNA analysis, differentially expressed genes (DEGs) and functional enrichments analyses revealed immune system aging signatures in Asian. These findings uncovered in which ways aging differentially affects the immune systems between Asian populations and discovered a common genetic variant that greatly impacts normal PBMC aging.