Hsd17b7

ENCODES a protein that exhibits estradiol 17-beta-dehydrogenase [NAD(P)+] activity; prolactin receptor binding; 3-keto sterol reductase activity (ortholog); INVOLVED IN estrogen biosynthetic process; hippocampus development; maternal process involved in female pregnancy; PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH polycystic ovary syndrome; gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol

编码一种具有雌二醇17-β脱氢酶[NAD(P)+]活性的蛋白质；催乳素受体结合；3-酮类固醇还原酶活性（同源）；参与雌激素生物合成过程；海马体发育；参与女性妊娠的母性过程；参与阿仑膦酸盐的药代动力学途径；胆固醇生物合成途径；胆固醇酯储存疾病途径；与多囊卵巢综合征相关；与胃肠道间质瘤（同源）相关；与甲状旁腺癌（同源）相关；存在于内质网（同源）；存在于内质网膜（同源）；存在于线粒体（同源）；与1,1,1-三氯-2,2-双(4-羟基苯基)乙烷、1-萘基异硫氰酸酯、17β-雌二醇相互作用。