γ- and β‑Peptide Foldamers from Common Multifaceted Building Blocks: Synthesis and Structural Characterization
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接:
https://figshare.com/articles/dataset/_and_Peptide_Foldamers_from_Common_Multifaceted_Building_Blocks_Synthesis_and_Structural_Characterization/2126332
下载链接
链接失效反馈官方服务:
资源简介:
Structural characterization of 3,4-disubstituted
γ-peptide
and 2,3-disubstituted β-peptide foldamers derived from common
multifaceted β-nitromethyl γ-amino acids and the chemical
transformation of the β-nitromethyl group in γ-peptides
into various functional derivatives are reported. The γ3,4-oligomers and α,γ-hybrid peptides showed characteristic
C14-and C12-helical conformations in single
crystals. Further, the new 2,3-disubstituted acyclic β-peptide
showed the C6-helical conformation despite the poor geometry
of H-bonds.
创建时间:
2016-02-13



