Worm Developmental Dynamics Database

This database is a collection of quantitative information about cell division dynamics in early Caenorhabditis elegans embryos when each of all essential embryonic genes is silenced individually by RNA interference (RNAi). The information is obtained by combining four-dimensional differential contrast interference (DIC) microscopy and computer image processing. The information collection provides novel opportunities for developing quantitative and computational approaches towards understanding animal development.本数据库收录了秀丽隐杆线虫（Caenorhabditis elegans）早期胚胎的细胞分裂动力学定量信息，相关数据采集自所有必需胚胎基因分别通过RNA干扰（RNA interference, RNAi）单独沉默的实验场景。此类信息通过结合四维微分干涉差（four-dimensional differential contrast interference, DIC）显微镜技术与计算机图像处理手段获取。本数据库为开发解析动物发育机制的定量与计算方法提供了全新契机。

搜集汇总

背景与挑战

背景概述

该数据集通过RNA干扰技术沉默线虫胚胎的所有关键基因，结合四维显微镜和计算机图像处理，收集了早期胚胎细胞分裂动态的定量信息。这些数据为开发定量和计算方法以理解动物发育提供了新的机会。