Gender_Functional_Connectivity_Dataset

fMRI dataset from 48 healthy men and women (20 F) undergoing emotion regulation task (view/suppress emotional reaction to emotional pictures) and self-reported negative affect behavioral data.

We were interested in whether men and women differed in their functional connectivity (FC) pattern while viewing versus regulating negative emotion induced by highly salient pictures, and whether this pattern related to their self-reported negative affect and suppression success. Despite women reporting more negative affect, both genders had comparable suppression success. Moreover, differences emerged between men and women’s FC patterns. During the regulation of negative emotion, better suppression in women was associated with stronger FC within a cingulo-opercular network, while men exhibited stronger FC within posterior regions of the ventral attentional network. We conclude that due to their propensity for higher emotional reactivity, women may employ a frontal top-down control network to downregulate negative emotion, while men may redirect attention away from the aversive stimulus by using posterior regions of the ventral attention network.

本数据集源自48名健康男女（其中女性20名）在执行情绪调节任务（观看/抑制情绪图片引起的情绪反应）以及自我报告的负面情绪行为数据的过程中所进行的fMRI（功能性磁共振成像）扫描。本研究旨在探究男性和女性在观看与调节由高度显著性图片引发的负面情绪时的功能连接（FC）模式是否存在差异，以及该模式是否与其自我报告的负面情绪及抑制成功度相关。尽管女性报告的负面情绪更多，但两性在抑制成功度上并无显著差异。此外，男性和女性的FC模式也呈现出显著差异。在调节负面情绪的过程中，女性较强的抑制效果与cingulo-opercular网络内部的更强功能连接相关，而男性则表现出ventral attentional网络后部区域更强的功能连接。据此，我们可以推断，由于女性较高的情绪反应倾向，她们可能通过前额叶自上而下的控制网络来下调负面情绪，而男性则可能通过使用ventral attentional网络的后部区域来转移对厌恶刺激的注意力。