Difamilast ointment in adult patients with atopic dermatitis: A phase 3 randomized double-blind vehicle-controlled trial

Supplementary Table I details the Investigator Global Assessment Score used to assess the primary endpoint. Supplementary Table Ⅱ lists the full exclusion criteria. Supplementary Table Ⅲ details the study investigators and study sites. Supplementary Fig 1 presents the percentage of patients with success in EASI 50, 75, and 90 at week 4 in difamilast and vehicle groups. Supplementary Fig 2 shows the least-square (LS) mean change in verbal rating scale (VRS) for pruritus score from baseline at each time point.