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Crystal Structure of KSR1:MEK1 in complex with AMP-PNP, and allosteric MEK inhibitor APS-9-95-1

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Protein Data Bank Japan2024-12-25 更新2026-03-21 收录
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Crystal Structure of KSR1:MEK1 in complex with AMP-PNP, and allosteric MEK inhibitor APS-9-95-1 Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 1, MAGNESIUM ION, ... Authors: Khan, Z.M, Dar, A.C, Scopton, A.P. Deposit date: 2020-08-20 Release date: 2020-09-30 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (3.62 Å) Cite: Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature, 588, 2020
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2020-08-20
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