Combining mTOR and JAK2 inhibitor resulted in synergistic inhibition of the proliferation rate (A) and clonogenic potential (B) of Ba/F3-EPOR VF and SET2 cells.

Data shown (mean ± SD) are from at least two experiments. The Combination Index (CI) was calculated as described in Materials and Methods. A CI<1 indicates that the interaction of the two drugs is synergistic. The first two columns report, for convenience, the IC50 value of the individual drugs in these experimental settings (see Results section for details).