Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-060
收藏Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-060 Descriptor: (2~{R})-2-azanyl-5-[[2-[[3-methyl-2,6-bis(oxidanylidene)-7-(phenylmethyl)purin-8-yl]methyl]-1~{H}-benzimidazol-5-yl]amino]-5-oxidanylidene-pentanoic acid, FE (III) ION, Tryptophan 5-hydroxylase 1 Authors: Schuetz, A, Mallow, K, Nazare, M, Specker, E, Heinemann, U. Deposit date: 2022-04-08 Release date: 2022-09-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.80888497598 Å) Cite: Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65, 2022
创建时间：
2022-04-08
