Ensembl GRCh38 ancestral sequences, bgzip-indexed for random access

The Ensembl human ancestral sequence for GRCh38, repackaged so that a single window can be read over HTTPS without downloading the whole set. Source. Ensembl Compara release 106, 10 primates EPO (2006). The sequence itself is unmodified: upper case marks a high-confidence ancestral call, lower case a low-confidence one, N a failure, '-' an insertion and '.' no coverage. What was changed. Each chromosome was bgzip-compressed and indexed (.fai and .gzi), and its sequence renamed from Ensembl's 'ANCESTOR_for_chromosome:GRCh38:22:1:50818468:1' form to the bare chromosome, so a caller can address a region without first knowing the chromosome length. 3.13 GB becomes 0.84 GB. Use. samtools faidx <url> 22:25000000-25000040, with the index supplied via --fai-idx and --gzi-idx. Indexes are distributed with the haploom software rather than here, because samtools resolves them relative to the data URL and Zenodo file URLs end in /content. Please cite Ensembl for the underlying data.