five

Transcriptional profiles of [ESI+]

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP155047
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资源简介:
We profile the transcriptional landscapes associated with acquisition of [ESI+], a prion scaffolded by Snt1, a core component of the Set3C histone deacetylase. We find that acquisition of [ESI+] leads to expression of otherwise silent, heterochromatic loci, proposing a new molecular means by which silent transcriptional states might be reversed. Overall design: mRNA sequencing of mid-logarithmically grown naïve and [ESI+] diploid cells
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2020-06-02
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