HCV NS3 Protease Domain with ketoamide inhibitor
收藏Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3kn2
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资源简介：
HCV NS3 Protease Domain with ketoamide inhibitor Descriptor: (1R,2S,5S)-3-{(2S)-2-(2,3-dihydro-1H-inden-2-yl)-2-[({(1S)-2,2-dimethyl-1-[(2-oxopiperidin-1-yl)methyl]propyl}carbamoyl)amino]acetyl}-6,6-dimethyl-N-{(1S)-1-[oxo(prop-2-en-1-ylamino)acetyl]butyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, HCV NS3 Protease Domain, Peptide KK-NS4A-KK, ... Authors: Nair, L.G, Sannigrahi, M, Pinto, P, Bogen, S, Chen, K.X, Njoroge, G, Prongay, A. Deposit date: 2009-11-11 Release date: 2010-01-19 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2009-11-11
