mRNA sequencing analysis of transcripts from CA1 regions 90 minutes after Long-Term Potentiation was induced

Conclusions: Our study illustrates the nature of the different transcripts in acute rat hippocampal slices after LTP 90 minutes was induced using field electrophysiology and compares them with control, unstimulated slices. Thius allowed us to identify wich genes are modulated in the hippocampus in order to promote and sustain LTP.结论：本研究借助场电位电生理技术（field electrophysiology）诱导急性大鼠海马脑片产生长时程增强（Long-term potentiation, LTP）并持续90分钟后，阐明了不同转录本（transcript）的表达特征，并将其与未受刺激的对照脑片进行对比。通过该实验设计，我们得以明确海马体内哪些基因的表达发生调控，从而促进并维持长时程增强。