Soft, wearable, microfluidic system for fluorometric analysis of loss of amino acids through eccrine sweat

Amino acids are essential for protein synthesis and metabolic processes in support of homeostatic balance and healthy body functions. This study quantitatively investigates eccrine sweat as a significant channel for loss of amino acids during exercise, to improve an understanding of amino acid turnover and to provide feedback to users on the need for supplement intake. The measurement platform consists of a soft, skin-interfaced microfluidic system for real-time analysis of amino acid content in eccrine sweat. This system relies on integrated fluorometric assays and smartphone-based imaging techniques for quantitative analysis, as a simple, cost-effective approach that does not require electrochemical sensors, electronics or batteries.  Human subject studies reveal substantial amino acid losses in sweat from working muscle regions during prolonged physical activities, thereby motivating the need for dietary supplementation. The findings suggest potential applications in healthcare..., , , # Soft, wearable, microfluidic system for fluorometric analysis of loss of amino acids through eccrine sweat

[Access this dataset on Dryad](https://doi.org/10.5061/dryad.95x69p8v0.)

## Description of the data and file structure

Data is structured as the title of the plot, headings including units, and data. Detailed descriptions for abbreviations and units can be found in the manuscript.

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* Fig.2: Fluorometric analysis of amino acid concentrations in sweat based on enzymatic assays. Fluorescence images and standard curves for total amino acid, alanine, and lysine show fluorescence as a function of concentration. Fluorometric results and those obtained by NMR for total amino acid, alanine, and lysine.

- Fig.3d-f: Time-dynamic analysis of total amino acid, alanine, and lysine in sweat before, during, and a...