ADA catalyzes the deamination of (deoxy)adenosine
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Cytosolic adenosine deaminase (ADA) catalyzes the hydrolysis of 2'deoxyadenosine and adenosine to yield deoxyinosine and inosine, respectively, plus ammonia (Akeson et al. 1988). Unpublished crystallographic data (PDB 3IAR) indicate that the human enzyme is a monomer.
细胞质腺苷脱氨酶(Cytosolic adenosine deaminase,简称ADA)催化2'-脱氧腺苷和腺苷的水解反应,分别生成脱氧肌苷和肌苷,同时产生氨(参见Akeson等人的研究,1988年)。未经发表的晶体学数据(PDB编号3IAR)表明,人类酶以单体形式存在。
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