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Genome-wide analysis of gene expression in LIF and LIF plus 2I in C57BL/6 mouse embryonic stem cells (B6 mESCs)

ChEBI2013-04-26 更新2026-07-21 收录

胚胎干细胞多能性

全基因组基因表达分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-46369 数据链接链接失效反馈

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资源简介：

Genome-wide analysis of gene expression in LIF and LIF plus 2I in C57BL/6 mouse embryonic stem cells (B6 mESCs)

应用场景：

创建时间：

2013-04-26

胚胎干细胞多能性

FOXO转录因子

Naïve pluripotency is sustained by a self-reinforcing gene regulatory network (GRN) comprising core and naïve pluripotency-specific transcription factors (TFs). Upon exiting naïve pluripotency, ES cel

NIAID Data Ecosystem80

Activin A in combination with ERK1/2 MAPK pathway inhibition sustains propagation of mouse embryonic stem cells

胚胎干细胞多能性

信号通路调控

The combination of Wnt pathway activation by the GSK3 inhibitor and ERK pathway inhibition by the MEK inhibitor, which is known as 2i is a well-established method to maintain mouse embryonic stem cell

NIAID Data Ecosystem40

Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency

胚胎干细胞多能性

发育阶段基因调控

In the mammalian embryo, epiblast cells must exit the naïve state and acquire formative pluripotency. This cell state transition is recapitulated by mouse embryonic stem cells (ESCs), which undergo pl

NIAID Data Ecosystem30

Rat embryonic stem cells produce fertile offspring through tetraploid complementation. Rat embryonic stem cells produce fertile offspring through tetraploid complementation

胚胎干细胞多能性

四倍体互补技术

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

Transcription profile of FBL-knock down ES cells. Mus musculus

胚胎干细胞多能性

核仁rRNA加工

Pluripotent stem cells have been shown to have unique nuclear properties, e.g., hyperdynamic chromatin and large, condensed nucleoli. However, the contribution of the latter unique nucleolar character

NIAID Data Ecosystem40

Genome-wide analysis of gene expression in LIF and LIF plus 2I in C57BL/6 mouse embryonic stem cells (B6 mESCs)

资源简介：

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