Insulin receptor associates with promoters genome-wide and regulates gene expression [ChIP-seq]. Insulin receptor associates with promoters genome-wide and regulates gene expression [ChIP-seq]

ChIP-seq analysis demonstrates an association of insulin receptor (IR) and RNA polymerase II on chromatin, with striking enrichment at gene promoters. Overall design: Examination of IR and RNA Pol II binding in HepG2 and SH-SY5Y cell lines (ChIP-seq).