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Split-APEX implicates splicing factor SRSF1 and splicing helicases in ribosomal biogenesis

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Figshare2025-09-26 更新2026-04-28 收录
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https://figshare.com/articles/dataset/_b_Split-APEX_implicates_splicing_factor_SRSF1_and_splicing_helicases_in_ribosomal_biogenesis_b_/30217723
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Scaffold files following mass spectrometry of proteins isolated on streptavidin beads following proximity biotinylation. This was done using (1 file) full-length APEX2 fused to the N-terminus of SRSF1 and (1 file) split-APEX, with complementary portions of APEX2 fused to the N-terminus of SRSF1 and to the N-terminus of helicases involved in pre-mRNA splicing. Experiments were done in triplicate.
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2025-09-26
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