Crystal Structure of a Pyrazolopyrimidine Inhibitor Bound to PI3 Kinase Gamma
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Crystal Structure of a Pyrazolopyrimidine Inhibitor Bound to PI3 Kinase Gamma Descriptor: 1-(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}phenyl)-3-pyridin-4-ylurea, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Bard, J, Svenson, K. Deposit date: 2009-07-15 Release date: 2009-09-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.798 Å) Cite: ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines. J.Med.Chem., 52, 2009
创建时间：
2009-07-15
