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Characterization and parental contribution of piRNAs and endo-siRNAs to mouse zygotes.

ChEBI2014-05-20 更新2026-07-21 收录

生殖细胞小RNA分析

胚胎表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45983 数据链接链接失效反馈

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资源简介：

Characterization and parental contribution of piRNAs and endo-siRNAs to mouse zygotes.

应用场景：

创建时间：

2014-05-20

胚胎表观遗传调控

基因组印记

Genomic imprinting and X chromosome inactivation (XCI) require epigenetic mechanisms to direct allele-specific expression. Despite their critical roles in embryonic development, how universal epigenet

NIAID Data Ecosystem70

Lactate regulates major zygotic genome activation by H3K18 lactylation in mammals [RNA-seq]

合子基因组激活

胚胎表观遗传调控

Lactate is present at a high level in the microenvironment of mammalian preimplantation embryos in vivo and in vitro. However, its role in preimplantation development is unclear. Here, we report that

NIAID Data Ecosystem40

Mus musculus Genome sequencing and assembly and Transcriptomics

胚胎表观遗传调控

重复序列沉默

SETDB1 is a key lysine methyltransferase (KMT) required in embryonic stem cells (ESCs), where it silences transposable elements and DNA repeats via histone H3 lysine 9 tri-methylation (H3K9me3), indep

NIAID Data Ecosystem40

Expression regulation by RYBP in mouse embryonic stem cells

胚胎表观遗传调控

Polycomb复合物功能研究

Polycomb repressive complexes (PRCs) are important chromatin regulators of ES cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B, and has been suggested to participate in l

NIAID Data Ecosystem70

Systematic Identification of Factors Crucial for Provirus Silencing in Embryonic Stem Cells (ChIP-seq)

前病毒沉默机制

胚胎表观遗传调控

Our study reports the first genome-wide atlas of functional nodes that mediate proviral silencing in ESCs. It provides evidences for the comprehensive, interconnected and multi-layered genetic/epigen

NIAID Data Ecosystem40

Characterization and parental contribution of piRNAs and endo-siRNAs to mouse zygotes.

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