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A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer

NIAID Data Ecosystem2026-03-07 收录

结直肠癌治疗

癌症药物临床试验

数据链接：

https://www.omicsdi.org/dataset/ecrin-mdr-crc/2138902 数据链接链接失效反馈

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资源简介：

This is an open label, multi-center, Phase 2 study of BBI608 in combination with cetuximab, panitumumab or capecitabine in patients with advanced colorectal cancer.

应用场景：

创建时间：

2012-03-15

结直肠癌治疗

药物剂量优化

Interventions: On Day 1, patients treated with FOLFIRI therapy received a 2-hour intravenous infusion of CPT-11 (150 mg/m2) combined with 1-LV (200 mg/m2), followed by a rapid intravenous infusion of

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Supplementary Table 2 from EGFR Blockade Reverts Resistance to KRAS G12C Inhibition in Colorectal Cancer

结直肠癌治疗

靶向抑制机制

Supplementary Table 2

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Table_1_Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: The REALIZE study.xlsx

腱鞘巨细胞瘤治疗

癌症药物临床试验

BackgroundA tenosynovial giant cell tumor (TGCT) is a locally aggressive benign neoplasm arising from intra- or extra-articular tissue, categorized as localized (L-TGCT, solitary lesion) and diffuse (

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Fuplatin: An Efficient and Low-Toxic Dual-Prodrug

抗癌药物研发

结直肠癌治疗

As FDA-approved chemotherapeutic agents, cisplatin, oxaliplatin, and 5-fluorouracil are widely used in clinic but limited by severe side-effects. To ameliorate their respective defects, a series of “d

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Discovery of 3,4-Dihydrobenzo[ f ][1,4]oxazepin-5(2 H )‑one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects

TNIK抑制剂开发

结直肠癌治疗

The Traf2- and Nck-interacting protein kinase (TNIK) is a downstream signal protein of the Wnt/β-catenin pathway and has been thought of as a potential target for the treatment of colorectal cancer (C

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A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer

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